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王钢论文《中国中西医结合肾病杂志》肾炎灵颗

来源:南京博大 时间:2014-10-30 20:57 点击: 次

文献出处:《中国中西医结合肾病杂志》2002年5月第3卷第5期

肾炎灵颗粒剂治疗难治性肾病综合征的临床研究

王 钢 曾安平 孙 伟 孔 薇  顾佐宁 

万晨旭  易 岚  邹燕勤

   目的: 评价肾炎灵颗粒剂治疗难治性肾病综合征的临床疗效及毒副反应。方法: 口服肾炎灵颗粒剂治疗65 例难治性肾病综合征患者4月~6月, 观察患者症状、体征变化和血生化、尿蛋白等检查结果以及与雷公藤多甙片副反应的对比。并对患者进行6 月~48 月的随访。结果: 肾炎灵颗粒剂对难治性肾病综合征近期总有效率为78.46%, 对肾功能有保护作用, 随访复发率仅为15.4%, 其常见副反应明显减少。结论: 肾炎灵颗粒剂对难治性肾病综合征有较好的治疗作用, 临床副反应明显低于雷公藤。

关键词 肾炎灵颗粒剂  难治性肾病综合征  中医药疗法

Treatment of Refractory Nephrotic Syndrome byShenyan Ling Granule

WANG Gang, ZENG Anping, SUN Wei , et al

Nep h rology Center , Jiang su H ospi tal of T radi tional Chinese

Medi cine, Nanj ing (210029)

ABSTRACT  Objective:To investigate the efficacy and adverse effects of ShenYanLing Granule in treating refractory

nephrot ic sy ndrome (RNS) .Methods: 65 patients w ith RNS received 4~ 6 mo nths of oral shen yan Ling Gr anule. Clinical

symptoms and signs, blood and ur inary biochemical analysis, and the adverse effects of tripter ygium wilfordii hook were

investigated. Patieuts w ere followed up for 6~ 48 months. Results: The to tal remission rate of shenyan Ling Granule in

treating RNS w as 78. 4% during t he first course( 2 months) . ShenYanLing Gr anule protected renal function. T he recurrent

rate was only 15. 4% during the follow up. The usual adverse effect decreased significantly. Conclusion: ShenYanLing

Granule has a comprehensive effect and few er adverse effect than tr ipteryg ium w ilfordii hook in treatment of RNS.

KEY WORDS   ShenYanLing Granule  Refr actory Nephrotic Sy ndrome

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